SNBL knows what your team needs to accurately assess your compound's potential for toxicity: quality data from regulatory compliant studies, with timely delivery and high ROI. Our team of experienced Study Directors delivers answers to your investigative questions using methods such as human lymphocyte chromosomal aberration tests, pathogen experiments with genetically engineered virus-vectors, and ELISA serum-antibody titer determinations. With a broad range of targeted, internationally recognized studies—from phototoxicity to implantation studies—we generate for you insights and informative data about your development molecules or devices.
Timeline for Reporting
1.5 to 2.5 months, from approval of the protocol until submission of the draft report (if pathological examinations are included, the testing period is 3.5 to 4 months)
SNBL conducts local irritation studies to investigate whether your pharmaceuticals, medical devices, chemical compounds, or agrochemicals irritate skin or muscle tissue, blood vessels, or mucosal tissues.
Both primary and cumulative irritation studies can encompass nasal, vaginal, rectal, and oral mucosa irritancy.
Antigenicity and Sensitization
In antigenicity and sensitization studies, we expose the test system to your compound, device, or agrochemical, and then investigate the inducibility of immediate and delayed allergies.
Eye irritation studies
We also have a wealth of experience in extensive ocular toxicity testing.
We also offer skin injury model studies and peritoneal dialysis model studies.
With a track record spanning decades and over a thousand studies, we can perform GLP-compliant tests for any regulatory agency.
Phototoxicity (in vivo, in vitro)
We have an outstanding record for 3T3 neutral red uptake (NRU) phototoxicity tests in vitro, and in vivo studies using guinea pigs, rats, and mice.
We are highly experienced in implanting medical devices into skin, muscle, and bone, also have experience with intraperitoneal implantation, vascular graft replacement, and dura mater replacement.
Experiments Using Pathogens
We perform biosafety studies in our dedicated facilities using non-human primates, rodents, and ferrets, including studies using genetically modified organisms (GMOs). We can also evaluate your vaccines with a wide variety of in vitro assays.