In response to the recent growing public concern for animal welfare, there has been an increasing need for imaging devices that allow in vivo, noninvasive, and temporal observations. In addition, many of our imaging devices are also used in clinical settings, so the data using these devices are expected to play an important role as novel biomarkers in clinical trials. Indeed, attempts are already being made to apply this technology to drug discovery from the approaches of both safety and efficacy.
In addition to the animal models introduced above, we can also offer flexible support for your projects, from the development of new disease models to pharmacological efficacy evaluations. Please feel free to contact us for more information.
Muscle Mass Measurement by MRI/DXA
By measuring muscle cross-sectional area (MRI) and lean mass (DXA), the effect of test article is evaluated in vivo, noninvasively and temporally. Three sites are measured for muscle cross-sectional area: the upper arm, lumber part, and femur (3 slices/ site); and it is possible to separately measure lean mass of the trunk and the limbs. In addition to muscle cross-sectional area, we are also investigating evaluation methods for muscle volume.
4-Slice Helical CT
Optical Coherence Tomography
Animal X-Ray CT
In Vivo Imaging System (IVIS)