Pharmacokinetics and Bioanalysis Center (SNBL PBC)


SNBL Pharmacokinetics and Bioanalysis Center (PBC), which is located in Kainan, Wakayama, Japan, offers establishment and validation of analytical methods, analysis of biological samples, and calculation of pharmacokinetics parameters by expert researchers using state-of-the-art equipment. We are able to expertly analyze a number of compounds such as test articles and metabolites in samples, and have conducted more than 1400 studies, using HPLC, LC-MS/MS, and ICP-MS and other instruments. SNBL PBC can propose the most suitable study design according to client drug development needs, including both small and large molecules.


SNBL can analyze both preclinical (several kinds of animals) and clinical (phase I to IV) study samples (plasma, urine, various body fluids and tissues) in compliance with GxP regulations.


• HPLC: Shimadzu (13), Waters (4)

• LC-MS/MS: Triple Quad 6500 (2), Qtrap 5500 (2), 4000 Qtrap (1), Triple Quad 5500 (1), API 5000 (5), API 4000 (20), API 3000 (3) from AB Sciex Orbitrap velos Pro (1), Vantage (1) from Thermo Fisher Scientific

• ICP-MS: 7700 (1), 7500 (1) from Agilent Technologies


If you would like to see the list of equipment at SNBL PBC, please click here.


SNBL PBC also offers ADME (absorption, distribution, metabolism and excretion) studies using radioisotope-labeled compounds.